To start, let’s look at where both shows take place, as the setting is an important element in both The Wire and Breaking Bad.
The Wire’s Setting: Baltimore
Baltimore is a city riddled with problems. You have the streets, the police department, the school system, and the news room. And then, you also have the docks, which are unique to Baltimore itself. Any of these places would make for an excellent setting, but The Wire highlights ALL of them. And it shows how everybody, in some way, is connected to one another in this problematic city. In truth, the setting itself is the main character of The Wire, which is kind of mind-blowing when you think about it.